In this blend of the B movie classic The Blob (1958) and some Romero's zombies film, a meteorite collides in a small town. Grant finds it, and is infected by a parasite worm, which installs in his brain and causes him a creepy transformation into a monster. Starla, his wife, and Bill, a policeman, will try to stop him and the plague of worms generated by the creature.
- NTSC Region 1
- Widescreen Edition
- Commentary by: Director James Gunn and actor Nathan FillionDolby Digital 5.1
- Deleted scenes
- Extended scenes
- Gag reel
- Bringing "Slither's" creatures to life
- Slithery set tour with Nathan Fillion
- "A Making Of": The sick minds and slimy days of "Slither"
- Feature commentary with director James Gunn and actor Nathan Fillion
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